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20% increase in natural GLP-1 level Blood glucose improvement (HbA1c, FBG, HOMA-IR) 24% prediabetic subjects back to normoglycemia PROVEN COMPATIBILITY with Metformin Randomized, Double-blind, Placebo-controlled, Crossover Trial 36 prediabetic subjects (18 - 65 years old) American Diabetes Association (HbA1c = 5.7 - 6.4%) Group A = 250mg Eriomin + 1000mg Metformin Group B = Placebo + 1000mg Metformin Clinically Demonstrated Efficacy Preserve Active GLP-1 Level Active GLP-1 are prone to inactivation by DPP-4 enzymes, inactivated GLP-1 cannot perform its function Effective Glucose Clearance Eriomin group has significant lower blood glucose level at both 60 min and 120 min Eriomin exhibited synergistic effect in combination with metformin , indicating potential for improved efficacy without an increase in adverse effects

The cost of these drugs in the US is almost 10 times more than other parts of the world and that has made it extremely challenging to be able to continue to provide coverage to everyone who wants to lose weight or can benefit from the drugs

Indeed, we now understand that GLP-1 controls inflammation (75), reduces experimental kidney injury (76), and like GLP-2, acts as a potent intestinal growth factor through mechanisms including stimulation of crypt fission (ref

Saadh, M

Pancreas 1987